Version 5.4
Homo sapiens Protein: RIMS1
Summary
InnateDB Protein IDBP-383155.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RIMS1
Protein Name regulating synaptic membrane exocytosis 1
Synonyms CORD7; RAB3IP2; RIM; RIM1;
Species Homo sapiens
Ensembl Protein ENSP00000402273
InnateDB Gene IDBG-92166 (RIMS1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005083 small GTPase regulator activity
GO:0005515 protein binding
GO:0017137 Rab GTPase binding
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006461 protein complex assembly
GO:0006886 intracellular protein transport
GO:0007268 synaptic transmission
GO:0007269 neurotransmitter secretion
GO:0007601 visual perception
GO:0014047 glutamate secretion
GO:0016079 synaptic vesicle exocytosis
GO:0017156 calcium ion-dependent exocytosis
GO:0045055 regulated secretory pathway
GO:0046903 secretion
GO:0050790 regulation of catalytic activity
GO:0050896 response to stimulus
GO:0061025 membrane fusion
Cellular Component
GO:0005886 plasma membrane
GO:0030054 cell junction
GO:0042734 presynaptic membrane
Protein Structure and Domains
PDB ID
InterPro IPR000008 C2 domain
PFAM PF00168
PRINTS PR00360
PIRSF
SMART SM00239
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86UR5
PhosphoSite PhosphoSite-Q86UR5
TrEMBL
UniProt Splice Variant
Entrez Gene 22999
UniGene Hs.608538
RefSeq NP_001161883
HUGO HGNC:17282
OMIM 606629
CCDS CCDS55033
HPRD 09435
IMGT
EMBL AB002338 AB045726 AB051866 AF263305 AF263306 AF263307 AF263308 AF263309 AF263310 AK294868 AK295001 AK296303 AK300853 AK309185 AL034373 AL035633 AL160405 AL390056 AL445256 AL590011 AY190519 BC151853 BC152435
GenPept AAG23162 AAG23163 AAG23164 AAG23165 AAG23166 AAG23167 AAI51854 AAI52436 AAO38848 BAA20798 BAB87121 BAB87242 BAH11906 BAH11945 BAH12309 BAH13358 CAI16961 CAI20558 CAI21554 CAI39598 CAI39600 CAI39604 CAI42135 CAI42139

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca