Version 5.4
Homo sapiens Protein: ARPC3
Summary
InnateDB Protein IDBP-383190.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARPC3
Protein Name actin related protein 2/3 complex, subunit 3, 21kDa
Synonyms ARC21; p21-Arc;
Species Homo sapiens
Ensembl Protein ENSP00000413221
InnateDB Gene IDBG-57068 (ARPC3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 41 [view]
Protein-Protein 41 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0030833 regulation of actin filament polymerization
GO:0034314 Arp2/3 complex-mediated actin nucleation
Cellular Component
GO:0005856 cytoskeleton
GO:0005885 Arp2/3 protein complex
Protein Structure and Domains
PDB ID
InterPro IPR007204 ARP2/3 complex, 21kDa subunit (p21-Arc)
PFAM PF04062
PRINTS
PIRSF PIRSF016315
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JZD1
UniProt Splice Variant
Entrez Gene 10094
UniGene Hs.609962
RefSeq
HUGO HGNC:706
OMIM 604225
CCDS
HPRD 09175
IMGT
EMBL AC144548
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca