Homo sapiens Protein: CLDN25
Summary
InnateDB Protein IDBP-383225.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLDN25
Protein Name claudin 25
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000396304
InnateDB Gene IDBG-307507 (CLDN25)
Protein Structure
UniProt Annotation
Function Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. {ECO:0000250}.
Subcellular Localization Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
Biological Process
Cellular Component
GO:0005886 plasma membrane
GO:0005923 tight junction
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR004031 PMP-22/EMP/MP20/Claudin superfamily
IPR006187 Claudin
PFAM PF00822
PF13903
PRINTS PR01077
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt C9JDP6
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 644672
UniGene Hs.705360
RefSeq NP_001094859
HUGO HGNC:37218
OMIM
CCDS CCDS44736
HPRD
IMGT
EMBL AP003170 CH471065
GenPept EAW67230