Homo sapiens Protein: CLDN25 | |||||||
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Summary | |||||||
InnateDB Protein | IDBP-383225.4 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | CLDN25 | ||||||
Protein Name | claudin 25 | ||||||
Synonyms | |||||||
Species | Homo sapiens | ||||||
Ensembl Protein | ENSP00000396304 | ||||||
InnateDB Gene | IDBG-307507 (CLDN25) | ||||||
Protein Structure |
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UniProt Annotation | |||||||
Function | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. {ECO:0000250}. | ||||||
Subcellular Localization | Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. | ||||||
Disease Associations | |||||||
Tissue Specificity | |||||||
Comments | |||||||
Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||
PDB ID | |||||||
InterPro |
IPR004031
PMP-22/EMP/MP20/Claudin superfamily IPR006187 Claudin |
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PFAM |
PF00822
PF13903 |
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PRINTS |
PR01077
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PIRSF | |||||||
SMART | |||||||
TIGRFAMs | |||||||
Post-translational Modifications | |||||||
Modification | |||||||
Cross-References | |||||||
SwissProt | C9JDP6 | ||||||
PhosphoSite | PhosphoSite- | ||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | 644672 | ||||||
UniGene | Hs.705360 | ||||||
RefSeq | NP_001094859 | ||||||
HUGO | HGNC:37218 | ||||||
OMIM | |||||||
CCDS | CCDS44736 | ||||||
HPRD | |||||||
IMGT | |||||||
EMBL | AP003170 CH471065 | ||||||
GenPept | EAW67230 | ||||||