Version 5.4
Homo sapiens Protein: BCL2L12
Summary
InnateDB Protein IDBP-383343.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BCL2L12
Protein Name BCL2-like 12 (proline rich)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000393803
InnateDB Gene IDBG-63278 (BCL2L12)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Expressed mainly in breast, thymus, prostate, fetal liver, colon, placenta, pancreas, small intestine, spinal cord, kidney, and bone marrow and to a lesser extent in many other tissues. Isoform 2 is primarily expressed in skeletal muscle.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process
Cellular Component
GO:0005634 nucleus
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9HB09
PhosphoSite PhosphoSite-Q9HB09
TrEMBL
UniProt Splice Variant
Entrez Gene 83596
UniGene Hs.289052
RefSeq NP_001035758
HUGO HGNC:13787
OMIM 610837
CCDS CCDS46144
HPRD 16543
IMGT
EMBL AC011495 AF289220 BC007724 BC104004 BC104005 BC104006
GenPept AAG29495 AAG29496 AAH07724 AAI04005 AAI04006 AAI04007

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca