Version 5.4
Homo sapiens Protein: CLSTN2
Summary
InnateDB Protein IDBP-384542.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLSTN2
Protein Name calsyntenin 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000402460
InnateDB Gene IDBG-58966 (CLSTN2)
Protein Structure
UniProt Annotation
Function May modulate calcium-mediated postsynaptic signals. {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Endoplasmic reticulum membrane. Golgi apparatus membrane. Note=Most prominent in the postsynaptic specializations of asymmetric (type I) synapses with both axodendritic and axospinous localization. {ECO:0000250}.
Disease Associations
Tissue Specificity Restricted to the brain. {ECO:0000269PubMed:12498782}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion
Cellular Component
GO:0000139 Golgi membrane
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0045211 postsynaptic membrane
Protein Structure and Domains
PDB ID
InterPro IPR002126 Cadherin
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR015919 Cadherin-like
PFAM PF00028
PRINTS PR00205
PIRSF
SMART SM00112
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H4D0
PhosphoSite PhosphoSite-Q9H4D0
TrEMBL B3KUA5
UniProt Splice Variant
Entrez Gene 64084
UniGene Hs.158529
RefSeq NP_071414
HUGO HGNC:17448
OMIM 611323
CCDS CCDS3112
HPRD 13077
IMGT
EMBL AC010181 AC048346 AC092988 AC108744 AC117390 AC117396 AC117449 AJ278018 AK096432 AK096818 AK315308 AY753303 BC004871 BC007943 BC103496 BC103506 BC104485 CH471052
GenPept AAH04871 AAH07943 AAI03497 AAI03507 AAI04486 AAV30553 BAG37712 BAG53289 BAG53367 CAC14924 EAW79018

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca