Homo sapiens Protein: SYPL1
Summary
InnateDB Protein IDBP-384924.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYPL1
Protein Name synaptophysin-like 1
Synonyms H-SP1; SYPL;
Species Homo sapiens
Ensembl Protein ENSP00000388336
InnateDB Gene IDBG-35231 (SYPL1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasmic vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Melanosome {ECO:0000269PubMed:17081065}. Note=Cytoplasmic transport vesicles (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
Biological Process
GO:0006810 transport
GO:0007268 synaptic transmission
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030285 integral component of synaptic vesicle membrane
GO:0030659 cytoplasmic vesicle membrane
GO:0042470 melanosome
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001285 Synaptophysin/synaptoporin
IPR008253 Marvel domain
PFAM PF01284
PRINTS PR00220
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q16563
PhosphoSite PhosphoSite-Q16563
TrEMBL
UniProt Splice Variant
Entrez Gene 6856
UniGene Hs.80919
RefSeq NP_874384
HUGO HGNC:11507
OMIM
CCDS CCDS47685
HPRD 15459
IMGT
EMBL AC005095 BC016835 BC020938 BC061887 CH236947 CH471070 S72481 X61382 X68194
GenPept AAB31344 AAD50513 AAH16835 AAH20938 AAH61887 CAA48276 EAL24402 EAW83380