InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SHOX2

Summary

InnateDB Protein

IDBP-385054.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SHOX2

Protein Name

short stature homeobox 2

Synonyms

OG12; OG12X; SHOT;

Species

Homo sapiens

Ensembl Protein

ENSP00000398704

InnateDB Gene

IDBG-62994 (SHOX2)

Protein Structure

UniProt Annotation

Function

May be a growth regulator and have a role in specifying neural systems involved in processing somatosensory information, as well as in face and body structure formation.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Expressed in heart, skeletal muscle, liver, lung, bone marrow fibroblast, pancreas and placenta.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000976	transcription regulatory region sequence-specific DNA binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity

Biological Process

GO:0001501	skeletal system development
GO:0006355	regulation of transcription, DNA-templated
GO:0007399	nervous system development
GO:0007507	heart development