Version 5.4
Homo sapiens Protein: SCHIP1
Summary
InnateDB Protein IDBP-385109.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCHIP1
Protein Name schwannomin interacting protein 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000404860
InnateDB Gene IDBG-63351 (SCHIP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm {ECO:0000269PubMed:10669747}. Note=Partially colocalizes with NF2 beneath the cytoplasmic membrane.
Disease Associations
Tissue Specificity Isoform 5 and isoform 6 are highly expressed in the brain. Both isoforms derive from naturally occurring readthrough transcripts which produce IQCJ-SCHIP1 fusion proteins. {ECO:0000269PubMed:17045569}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR015649 Schwannomin interacting protein 1
PFAM PF10148
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9P0W5
PhosphoSite PhosphoSite-Q9P0W5
TrEMBL
UniProt Splice Variant
Entrez Gene 29970
UniGene Hs.730166
RefSeq NP_001184038
HUGO HGNC:15678
OMIM
CCDS CCDS56294
HPRD 15302
IMGT
EMBL AF070614 AF145713 AF145714 AF145715 AK091871 BC005947 BC036535 CH471052 DQ157847 DQ157848
GenPept AAC25386 AAF34241 AAF34242 AAF34243 AAH05947 AAH36535 ABA42889 ABA42890 BAG52432 EAW78662

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca