Version 5.4
Homo sapiens Protein: ISOC2
Summary
InnateDB Protein IDBP-385430.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ISOC2
Protein Name isochorismatase domain containing 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000401726
InnateDB Gene IDBG-70752 (ISOC2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Mitochondrion {ECO:0000250}. Cytoplasm {ECO:0000269PubMed:17658461}. Nucleus {ECO:0000269PubMed:17658461}. Note=Localizes to the nucleus in the presence of CDKN2A.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0005515 protein binding
Biological Process
GO:0008152 metabolic process
GO:0031648 protein destabilization
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID
InterPro IPR000868 Isochorismatase-like
PFAM PF00857
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96AB3
PhosphoSite PhosphoSite-Q96AB3
TrEMBL K7ENV7
UniProt Splice Variant
Entrez Gene 79763
UniGene Hs.467306
RefSeq NP_001129673
HUGO HGNC:26278
OMIM 612928
CCDS CCDS46195
HPRD 08030
IMGT
EMBL AC008735 AC135592 AK027122 AK131324 BC017344 CH471135 CR457377
GenPept AAH17344 BAB15666 BAD18484 CAG33658 EAW72379

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca