Version 5.4
Homo sapiens Protein: ASB15
Summary
InnateDB Protein IDBP-385969.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ASB15
Protein Name ankyrin repeat and SOCS box containing 15
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000401166
InnateDB Gene IDBG-38894 (ASB15)
Protein Structure
UniProt Annotation
Function May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
GO:0035556 intracellular signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002110 Ankyrin repeat
IPR020683 Ankyrin repeat-containing domain
PFAM PF00023
PF13606
PF11929
PF12796
PRINTS PR01415
PIRSF
SMART SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8WXK1
PhosphoSite PhosphoSite-Q8WXK1
TrEMBL C9J956
UniProt Splice Variant
Entrez Gene 142685
UniGene Hs.83916
RefSeq
HUGO HGNC:19767
OMIM
CCDS
HPRD 10669
IMGT
EMBL AC006333 AF403033 AK125360 BC100874 BC100875 BC100876 BC100877 CR749595
GenPept AAI00875 AAI00876 AAI00877 AAI00878 AAL57352 BAC86146 CAH18393

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca