Homo sapiens Protein: LMOD2
Summary
InnateDB Protein IDBP-385977.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LMOD2
Protein Name leiomodin 2 (cardiac)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000411932
InnateDB Gene IDBG-38923 (LMOD2)
Protein Structure
UniProt Annotation
Function May block the elongation and depolymerization of the actin filaments at the pointed end. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity Specifically expressed in heart and skeletal muscles. Not expressed in other tissues. {ECO:0000269PubMed:11318603}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005523 tropomyosin binding
Biological Process
GO:0051694 pointed-end actin filament capping
Cellular Component
GO:0005856 cytoskeleton
Protein Structure and Domains
PDB ID
InterPro IPR003124 WH2 domain
IPR004934 Tropomodulin
PFAM PF02205
PF03250
PRINTS
PIRSF
SMART SM00246
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6P5Q4
PhosphoSite PhosphoSite-Q6P5Q4
TrEMBL B4DUL7
UniProt Splice Variant
Entrez Gene 442721
UniGene Hs.592260
RefSeq NP_997046
HUGO HGNC:6648
OMIM 608006
CCDS CCDS47693
HPRD
IMGT
EMBL AK300698 BC017911 BC062765 CH236947
GenPept AAH17911 AAH62765 BAG62379 EAL24334 EAL24335