InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: EIF4G1

Summary

InnateDB Protein

IDBP-386130.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EIF4G1

Protein Name

eukaryotic translation initiation factor 4 gamma, 1

Synonyms

EIF-4G1; EIF4F; EIF4G; EIF4GI; P220; PARK18;

Species

Homo sapiens

Ensembl Protein

ENSP00000411826

InnateDB Gene

IDBG-67809 (EIF4G1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 96 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	96 [view]
Protein-Protein	95 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003743	translation initiation factor activity
GO:0005488	binding
GO:0005515	protein binding
GO:0008135	translation factor activity, nucleic acid binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
GO:0006412	translation
GO:0006413	translational initiation
GO:0006446	regulation of translational initiation
GO:0008219	cell death
GO:0008286	insulin receptor signaling pathway
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019221	cytokine-mediated signaling pathway
GO:0044267	cellular protein metabolic process