Version 5.4
Homo sapiens Protein: DARS
Summary
InnateDB Protein IDBP-386196.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DARS
Protein Name aspartyl-tRNA synthetase
Synonyms aspRS; HBSL;
Species Homo sapiens
Ensembl Protein ENSP00000387508
InnateDB Gene IDBG-70984 (DARS)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 59 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 59 [view]
Protein-Protein 57 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004815 aspartate-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006422 aspartyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb
IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N)
IPR006195 Aminoacyl-tRNA synthetase, class II
PFAM PF00152
PRINTS PR01042
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H7BZ35
UniProt Splice Variant
Entrez Gene 1615
UniGene Hs.602640
RefSeq
HUGO HGNC:2678
OMIM 603084
CCDS
HPRD 04361
IMGT
EMBL AC011999 AC093391
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca