InnateDB Protein
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IDBP-386347.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ETV5
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Protein Name
|
ets variant 5
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Synonyms
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ERM;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000413755
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InnateDB Gene
|
IDBG-408468 (ETV5)
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Protein Structure
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Function |
Binds to DNA sequences containing the consensus nucleotide core sequence GGAA.
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Subcellular Localization |
Nucleus.
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Disease Associations |
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Tissue Specificity |
Ubiquitous.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
20
[view]
|
Protein-Protein |
18
[view]
|
Protein-DNA |
1
[view]
|
Protein-RNA |
1
[view]
|
DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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|
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Molecular Function |
Accession |
GO Term |
GO:0000977
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RNA polymerase II regulatory region sequence-specific DNA binding
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GO:0000981
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sequence-specific DNA binding RNA polymerase II transcription factor activity
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GO:0001228
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RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
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GO:0003677
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DNA binding
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GO:0003700
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sequence-specific DNA binding transcription factor activity
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GO:0043565
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sequence-specific DNA binding
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GO:0044212
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transcription regulatory region DNA binding
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Biological Process |
GO:0006355
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regulation of transcription, DNA-templated
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GO:0006357
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regulation of transcription from RNA polymerase II promoter
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GO:0006366
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transcription from RNA polymerase II promoter
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GO:0030154
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cell differentiation
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GO:0034599
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cellular response to oxidative stress
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GO:0045944
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positive regulation of transcription from RNA polymerase II promoter
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|
Cellular Component |
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PDB ID |
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InterPro |
IPR000418
Ets domain
IPR006715
PEA3-type ETS-domain transcription factor, N-terminal
|
PFAM |
PF00178
PF04621
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PRINTS |
PR00454
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PIRSF |
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SMART |
SM00413
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TIGRFAMs |
|
Modification |
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SwissProt |
P41161
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PhosphoSite |
PhosphoSite-P41161
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TrEMBL |
C9JMF0
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UniProt Splice Variant |
|
Entrez Gene |
2119
|
UniGene |
Hs.619212
|
RefSeq |
|
HUGO |
HGNC:3494
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OMIM |
601600
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CCDS |
CCDS33906
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HPRD |
09035
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IMGT |
|
EMBL |
AC108671
AC112649
AC131156
AK301878
BC007333
BT006713
CH471052
CR456767
X76184
X96375
X96376
X96377
X96378
X96379
X96380
X96381
X96382
|
GenPept |
AAH07333
AAP35359
BAH13573
CAA53778
CAA65246
CAG33048
EAW78200
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