Version 5.4
Homo sapiens Protein: C10orf90
Summary
InnateDB Protein IDBP-386834.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol C10orf90
Protein Name chromosome 10 open reading frame 90
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000405995
InnateDB Gene IDBG-93103 (C10orf90)
Protein Structure
UniProt Annotation
Function Tumor suppressor that is required to sustain G2/M checkpoint after DNA damage. Mediates CDKN1A/p21 protein stability in a ubiquitin-independent manner (By similarity). May have a role in the assembly of primary cilia. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:20844083}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269PubMed:20844083}. Note=Localizes to the actin cytoskeleton in a proportion of cells. Colocalizes with centriolar acetylated tubulin.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q96M02
TrEMBL S4R3N7
UniProt Splice Variant
Entrez Gene 118611
UniGene Hs.587663
RefSeq XP_006717678
HUGO HGNC:26563
OMIM
CCDS
HPRD 16587
IMGT
EMBL AL392108 AL583860 AL589787
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca