InnateDB Protein
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IDBP-386835.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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XXYLT1
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Protein Name
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chromosome 3 open reading frame 21
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000409865
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InnateDB Gene
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IDBG-70485 (XXYLT1)
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Protein Structure
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Function |
Alpha-1,3-xylosyltransferase, which elongates the O- linked xylose-glucose disaccharide attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of the second xylose. {ECO:0000269PubMed:22117070}.
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Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000269PubMed:22117070}; Single-pass type II membrane protein {ECO:0000269PubMed:22117070}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0016757
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transferase activity, transferring glycosyl groups
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GO:0016763
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transferase activity, transferring pentosyl groups
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR002495
Glycosyl transferase, family 8
IPR029044
Nucleotide-diphospho-sugar transferases
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PFAM |
PF01501
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8NBI6
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PhosphoSite |
PhosphoSite-Q8NBI6
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
152002
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UniGene |
Hs.478741
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RefSeq |
XP_005269344
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HUGO |
HGNC:26639
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OMIM |
614552
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CCDS |
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HPRD |
08757
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IMGT |
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EMBL |
AK057046
AK075551
AK092474
BC019036
BC039067
CH471052
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GenPept |
AAH19036
AAH39067
BAB71355
BAC03899
BAC11694
EAW78028
EAW78029
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