InnateDB Protein
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IDBP-387279.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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REPIN1
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Protein Name
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replication initiator 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000388287
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InnateDB Gene
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IDBG-235722 (REPIN1)
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Protein Structure
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Function |
Sequence-specific double-stranded DNA-binding protein required for initiation of chromosomal DNA replication. Binds on 5'-ATT-3' reiterated sequences downstream of the origin of bidirectional replication (OBR) and a second, homologous ATT sequence of opposite orientation situated within the OBR zone. Facilitates DNA bending.
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Subcellular Localization |
Nucleus {ECO:0000269PubMed:10606657}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
21
[view]
|
Protein-Protein |
20
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR007087
Zinc finger, C2H2
IPR015880
Zinc finger, C2H2-like
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PFAM |
PF00096
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PRINTS |
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PIRSF |
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SMART |
SM00355
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TIGRFAMs |
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Modification |
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SwissProt |
Q9BWE0
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PhosphoSite |
PhosphoSite-Q9BWE0
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TrEMBL |
E7EVL6
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UniProt Splice Variant |
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Entrez Gene |
29803
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UniGene |
Hs.735782
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RefSeq |
NP_055189
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HUGO |
HGNC:17922
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OMIM |
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CCDS |
CCDS43677
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HPRD |
17966
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IMGT |
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EMBL |
AC005586
AF201303
AJ245553
BC000363
BC001760
CH471173
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GenPept |
AAF26712
AAH00363
AAH01760
AAS00385
AAS00386
CAB53100
EAW54117
EAW54118
EAW54119
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