Version 5.4
Homo sapiens Protein: TMEM176B
Summary
InnateDB Protein IDBP-387314.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM176B
Protein Name transmembrane protein 176B
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000413531
InnateDB Gene IDBG-48157 (TMEM176B)
Protein Structure
UniProt Annotation
Function May play a role in the process of maturation of dendritic cells. Required for the development of cerebellar granule cells (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in lung and dermal fibroblasts. {ECO:0000269PubMed:9922225}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0009887 organ morphogenesis
GO:0030154 cell differentiation
Cellular Component
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID
InterPro IPR007237 CD20-like
IPR016196 Major facilitator superfamily domain, general substrate transporter
PFAM PF04103
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3YBM2
PhosphoSite PhosphoSite-Q3YBM2
TrEMBL
UniProt Splice Variant
Entrez Gene 28959
UniGene Hs.647090
RefSeq NP_001094782
HUGO HGNC:29596
OMIM 610385
CCDS CCDS5908
HPRD 17443
IMGT
EMBL AC006479 AF115384 AK129525 AK315575 BC004358 BC014586 BC091471 CH471173 DQ144974
GenPept AAD23440 AAH04358 AAH14586 AAH91471 AAZ75648 BAG37949 EAW54077 EAW54078 EAW54079 EAW54080

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca