Version 5.4
Homo sapiens Protein: SLC13A1
Summary
InnateDB Protein IDBP-38751.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC13A1
Protein Name solute carrier family 13 (sodium/sulfate symporters), member 1
Synonyms NAS1; NaSi-1;
Species Homo sapiens
Ensembl Protein ENSP00000194130
InnateDB Gene IDBG-38749 (SLC13A1)
Protein Structure
UniProt Annotation
Function Sodium/sulfate cotransporter that mediates sulfate reabsorption in the kidney.
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Highly expressed in kidney; not detectable in the other tissues tested.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0008271 secondary active sulfate transmembrane transporter activity
GO:0015382 sodium:sulfate symporter activity
Biological Process
GO:0006814 sodium ion transport
GO:0008272 sulfate transport
GO:0035725 sodium ion transmembrane transport
GO:0055085 transmembrane transport
GO:1902358 sulfate transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001898 Sodium/sulphate symporter
IPR004680 Citrate transporter-like domain
PFAM PF00939
PF03600
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BZW2
PhosphoSite PhosphoSite-
TrEMBL Q75MH3
UniProt Splice Variant
Entrez Gene 6561
UniGene Hs.489849
RefSeq NP_071889
HUGO HGNC:10916
OMIM 606193
CCDS CCDS5786
HPRD 08394
IMGT
EMBL AC073054 AC091319 AF260824 AK026413 AK314537 CH236947 CH471070
GenPept AAG60583 AAS01993 AAS01997 BAB15477 BAG37127 EAL24337 EAW83582

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca