Version 5.4
Homo sapiens Protein: FKBP7
Summary
InnateDB Protein IDBP-387803.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FKBP7
Protein Name FK506 binding protein 7
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000415486
InnateDB Gene IDBG-76052 (FKBP7)
Protein Structure
UniProt Annotation
Function PPIases accelerate the folding of proteins during protein synthesis.
Subcellular Localization Endoplasmic reticulum lumen {ECO:0000255PROSITE-ProRule:PRU10138}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0005509 calcium ion binding
GO:0005528 FK506 binding
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding
GO:0061077 chaperone-mediated protein folding
Cellular Component
GO:0005788 endoplasmic reticulum lumen
GO:0005789 endoplasmic reticulum membrane
Protein Structure and Domains
PDB ID
InterPro IPR001179 Peptidyl-prolyl cis-trans isomerase, FKBP-type, domain
IPR002048 EF-hand domain
PFAM PF00254
PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y680
PhosphoSite PhosphoSite-Q9Y680
TrEMBL
UniProt Splice Variant
Entrez Gene 51661
UniGene Hs.410378
RefSeq NP_001128684
HUGO HGNC:3723
OMIM 607062
CCDS CCDS46462
HPRD 08451
IMGT
EMBL AC009948 AF092137 AF100751 AK292145 AY353086 AY359015 BC009711 BT007122
GenPept AAD40379 AAD43015 AAH09711 AAP35786 AAQ57208 AAQ89374 AAX88883 BAF84834

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca