Version 5.4
Homo sapiens Protein: MTHFD1L
Summary
InnateDB Protein IDBP-387819.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MTHFD1L
Protein Name methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
Synonyms dJ292B18.2; FTHFSDC1; MTC1THFS;
Species Homo sapiens
Ensembl Protein ENSP00000395158
InnateDB Gene IDBG-97919 (MTHFD1L)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004329 formate-tetrahydrofolate ligase activity
GO:0005524 ATP binding
Biological Process
GO:0009396 folic acid-containing compound biosynthetic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000559 Formate-tetrahydrofolate ligase, FTHFS
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF01268
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q4VXV2
UniProt Splice Variant
Entrez Gene 25902
UniGene
RefSeq
HUGO HGNC:21055
OMIM 611427
CCDS
HPRD 09967
IMGT
EMBL AL035086 AL049694 AL133260
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca