Version 5.4
Homo sapiens Protein: IPCEF1
Summary
InnateDB Protein IDBP-387978.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IPCEF1
Protein Name interaction protein for cytohesin exchange factors 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000394751
InnateDB Gene IDBG-98215 (IPCEF1)
Protein Structure
UniProt Annotation
Function Enhances the promotion of guanine-nucleotide exchange by PSCD2 on ARF6 in a concentration-dependent manner. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Translocated with PSCD2 to the plasma membrane upon epidermal growth factor (EGF) stimulation. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004601 peroxidase activity
GO:0005344 oxygen transporter activity
Biological Process
GO:0006979 response to oxidative stress
GO:0015671 oxygen transport
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR001849 Pleckstrin homology domain
PFAM PF00169
PRINTS
PIRSF
SMART SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8WWN9
PhosphoSite PhosphoSite-Q8WWN9
TrEMBL G3V132
UniProt Splice Variant
Entrez Gene 26034
UniGene Hs.146100
RefSeq NP_001124171
HUGO HGNC:21204
OMIM
CCDS CCDS47509
HPRD 17851
IMGT
EMBL AB007863 AJ310566 AK289917 AL033376 AL132774 AL445220 BC105015 BC105043 BC143623 BC143629 BX647254 CH471051
GenPept AAI05016 AAI05044 AAI43624 AAI43630 BAA23699 BAF82606 CAC83949 CAH72408 CAI20459 CAI46054 EAW47701 EAW47702

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca