InnateDB Protein
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IDBP-388.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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EIF1AY
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Protein Name
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eukaryotic translation initiation factor 1A, Y-linked
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000354722
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InnateDB Gene
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IDBG-384 (EIF1AY)
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Protein Structure
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Function |
Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). {ECO:0000250}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
Ubiquitous.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
5
[view]
|
Protein-Protein |
5
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001253
Translation initiation factor 1A (eIF-1A)
IPR006196
RNA-binding domain, S1, IF1 type
IPR012340
Nucleic acid-binding, OB-fold
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PFAM |
PF01176
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PRINTS |
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PIRSF |
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SMART |
SM00652
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TIGRFAMs |
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Modification |
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SwissProt |
O14602
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PhosphoSite |
PhosphoSite-O14602
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
9086
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UniGene |
Hs.604681
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RefSeq |
NP_004672
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HUGO |
HGNC:3252
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OMIM |
400014
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CCDS |
CCDS14795
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HPRD |
02455
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IMGT |
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EMBL |
AF000987
BC005248
BT007201
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GenPept |
AAC51834
AAH05248
AAP35865
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