InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SF3B1

Summary

InnateDB Protein

IDBP-388172.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SF3B1

Protein Name

splicing factor 3b, subunit 1, 155kDa

Synonyms

Hsh155; MDS; PRP10; PRPF10; SAP155; SF3b155;

Species

Homo sapiens

Ensembl Protein

ENSP00000402997

InnateDB Gene

IDBG-77902 (SF3B1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 171 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	171 [view]
Protein-Protein	168 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	2 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000375	RNA splicing, via transesterification reactions
GO:0000398	mRNA splicing, via spliceosome
GO:0008380	RNA splicing
GO:0010467	gene expression

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005681	spliceosomal complex
GO:0005689	U12-type spliceosomal complex
GO:0016607	nuclear speck
GO:0043231	intracellular membrane-bounded organelle
GO:0071013	catalytic step 2 spliceosome