InnateDB Protein
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IDBP-388296.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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NDUFB3
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Protein Name
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NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
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Synonyms
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B12; CI-B12;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000407336
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InnateDB Gene
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IDBG-78368 (NDUFB3)
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Protein Structure
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Function |
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
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Subcellular Localization |
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
8
[view]
|
Protein-Protein |
5
[view]
|
Protein-DNA |
3
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0008137
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NADH dehydrogenase (ubiquinone) activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR012576
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
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PFAM |
PF08122
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O43676
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PhosphoSite |
PhosphoSite-O43676
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TrEMBL |
C9JKQ2
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UniProt Splice Variant |
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Entrez Gene |
4709
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UniGene |
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RefSeq |
XP_006712607
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HUGO |
HGNC:7698
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OMIM |
603839
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CCDS |
CCDS2336
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HPRD |
11954
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IMGT |
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EMBL |
AC007272
AF035839
AF047183
BC018183
CH471063
CR456924
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GenPept |
AAC04268
AAC15590
AAH18183
AAX88972
CAG33205
EAW70233
EAW70234
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