Version 5.4
Homo sapiens Protein: KIF25
Summary
InnateDB Protein IDBP-388315.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KIF25
Protein Name kinesin family member 25
Synonyms KNSL3;
Species Homo sapiens
Ensembl Protein ENSP00000388878
InnateDB Gene IDBG-99160 (KIF25)
Protein Structure
UniProt Annotation
Function Negative regulator of amino acid starvation-induced autophagy. {ECO:0000269PubMed:22354037}.
Subcellular Localization Cytoplasm, cytoskeleton {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0000070 mitotic sister chromatid segregation
GO:0006996 organelle organization
GO:0007018 microtubule-based movement
GO:0008152 metabolic process
GO:0010507 negative regulation of autophagy
Cellular Component
GO:0005737 cytoplasm
GO:0005871 kinesin complex
GO:0005874 microtubule
Protein Structure and Domains
PDB ID
InterPro IPR001752 Kinesin, motor domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00225
PRINTS PR00380
PIRSF
SMART SM00129
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UIL4
PhosphoSite PhosphoSite-Q9UIL4
TrEMBL
UniProt Splice Variant
Entrez Gene 3834
UniGene Hs.668328
RefSeq
HUGO HGNC:6390
OMIM 603815
CCDS CCDS5305
HPRD 04818
IMGT
EMBL AB012722 AB012723 AL589733
GenPept BAA36417 BAA36418 CAI12327

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca