Version 5.4
Homo sapiens Protein: HAS3
Summary
InnateDB Protein IDBP-38837.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HAS3
Protein Name hyaluronan synthase 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000304440
InnateDB Gene IDBG-38833 (HAS3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0050501 hyaluronan synthase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0030203 glycosaminoglycan metabolic process
GO:0030212 hyaluronan metabolic process
GO:0030213 hyaluronan biosynthetic process
GO:0044281 small molecule metabolic process
GO:0045226 extracellular polysaccharide biosynthetic process
GO:0045893 positive regulation of transcription, DNA-templated
GO:0085029 extracellular matrix assembly
GO:1900106 positive regulation of hyaluranon cable assembly
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
GO:0036117 hyaluranon cable
Protein Structure and Domains
PDB ID
InterPro IPR001173 Glycosyltransferase 2-like
IPR029044 Nucleotide-diphospho-sugar transferases
PFAM PF00535
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O00219
PhosphoSite PhosphoSite-O00219
TrEMBL H3BRH5
UniProt Splice Variant
Entrez Gene 3038
UniGene Hs.592069
RefSeq NP_005320
HUGO HGNC:4820
OMIM 602428
CCDS CCDS10871
HPRD 03889
IMGT
EMBL AC009027 AF232772 AK291400 BC021853 CH471092 FJ648810 FJ648811 U86409
GenPept AAC51209 AAF36984 AAH21853 ACN41863 ACN41864 BAF84089 EAW83247 EAW83248

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca