InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NDUFS1

Summary

InnateDB Protein

IDBP-388556.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NDUFS1

Protein Name

NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)

Synonyms

CI-75k; CI-75Kd; PRO1304;

Species

Homo sapiens

Ensembl Protein

ENSP00000400976

InnateDB Gene

IDBG-79438 (NDUFS1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	47 [view]
Protein-Protein	44 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008137	NADH dehydrogenase (ubiquinone) activity
GO:0016491	oxidoreductase activity
GO:0016651	oxidoreductase activity, acting on NAD(P)H
GO:0051536	iron-sulfur cluster binding

Biological Process

GO:0042773	ATP synthesis coupled electron transport
GO:0055114	oxidation-reduction process

Cellular Component

GO:0016020

membrane

Protein Structure and Domains

PDB ID

InterPro

IPR006656 Molybdopterin oxidoreductase
IPR010228 NADH:ubiquinone oxidoreductase, subunit G
IPR015405 NADH-quinone oxidoreductase, chain G, C-terminal
IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding

PFAM

PF00384
PF09326
PF10588

PRINTS

PIRSF

SMART

SM00929

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite