Version 5.4
Homo sapiens Protein: PIKFYVE
Summary
InnateDB Protein IDBP-388658.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIKFYVE
Protein Name phosphoinositide kinase, FYVE finger containing
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000405736
InnateDB Gene IDBG-79756 (PIKFYVE)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005524 ATP binding
GO:0046872 metal ion binding
Biological Process
GO:0035556 intracellular signal transduction
GO:0044267 cellular protein metabolic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000306 FYVE zinc finger
IPR000591 DEP domain
IPR002423 Chaperonin Cpn60/TCP-1
IPR011011 Zinc finger, FYVE/PHD-type
IPR017455 Zinc finger, FYVE-related
IPR027409 GroEL-like apical domain
PFAM PF01363
PF00610
PF00118
PRINTS
PIRSF
SMART SM00064
SM00049
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9PDH4
UniProt Splice Variant
Entrez Gene 200576
UniGene Hs.732047
RefSeq
HUGO HGNC:23785
OMIM 609414
CCDS
HPRD 17852
IMGT
EMBL AC012362 AC016697
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca