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InnateDB Protein
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IDBP-388760.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ATIC
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Protein Name
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5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
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Synonyms
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AICAR; AICARFT; HEL-S-70p; IMPCHASE; PURH;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000388675
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InnateDB Gene
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IDBG-80213 (ATIC)
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Protein Structure
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| Function |
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| Subcellular Localization |
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 50 experimentally validated interaction(s) in this database.
| Experimentally validated |
| Total |
50
[view]
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| Protein-Protein |
50
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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Molecular Function |
| Accession |
GO Term |
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GO:0003937
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IMP cyclohydrolase activity
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GO:0004643
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phosphoribosylaminoimidazolecarboxamide formyltransferase activity
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| Biological Process |
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR011607
Methylglyoxal synthase-like domain
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| PFAM |
PF02142
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| PRINTS |
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| PIRSF |
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| SMART |
SM00851
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
F8WEF0
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| UniProt Splice Variant |
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| Entrez Gene |
471
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| UniGene |
Hs.90280
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| RefSeq |
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| HUGO |
HGNC:794
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| OMIM |
601731
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| CCDS |
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| HPRD |
03434
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| IMGT |
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| EMBL |
AC073284
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| GenPept |
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Version 5.4