InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GBA

Summary

InnateDB Protein

IDBP-388880.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GBA

Protein Name

glucosidase, beta, acid

Synonyms

GBA1; GCB; GLUC;

Species

Homo sapiens

Ensembl Protein

ENSP00000402577

InnateDB Gene

IDBG-103191 (GBA)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	17 [view]
Protein-Protein	17 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004348	glucosylceramidase activity
GO:0005102	receptor binding
GO:0005515	protein binding

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006665	sphingolipid metabolic process
GO:0006680	glucosylceramide catabolic process
GO:0006687	glycosphingolipid metabolic process
GO:0008219	cell death
GO:0023021	termination of signal transduction
GO:0032715	negative regulation of interleukin-6 production
GO:0035307	positive regulation of protein dephosphorylation
GO:0043407	negative regulation of MAP kinase activity
GO:0044281	small molecule metabolic process
GO:0046512	sphingosine biosynthetic process
GO:0046513	ceramide biosynthetic process
GO:0050728	negative regulation of inflammatory response
GO:0071356	cellular response to tumor necrosis factor