Version 5.4
Homo sapiens Protein: RAB7L1
Summary
InnateDB Protein IDBP-389954.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RAB7L1
Protein Name RAB7, member RAS oncogene family-like 1
Synonyms RAB7L; RAB7L1;
Species Homo sapiens
Ensembl Protein ENSP00000416613
InnateDB Gene IDBG-106171 (RAB7L1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0007030 Golgi organization
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0035526 retrograde transport, plasma membrane to Golgi
GO:0090316 positive regulation of intracellular protein transport
Cellular Component
GO:0005737 cytoplasm
GO:0005802 trans-Golgi network
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001806 Small GTPase superfamily
IPR003579 Small GTPase superfamily, Rab type
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00071
PRINTS PR00449
PIRSF
SMART SM00175
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O14966
PhosphoSite PhosphoSite-O14966
TrEMBL
UniProt Splice Variant
Entrez Gene 8934
UniGene Hs.603513
RefSeq NP_001129136
HUGO HGNC:9789
OMIM 603949
CCDS CCDS44302
HPRD 11962
IMGT
EMBL AC119673 AK303879 AK308359 BC002585 D84488
GenPept AAH02585 BAA22160 BAG64815

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca