Version 5.4
Homo sapiens Protein: PDF
Summary
InnateDB Protein IDBP-39045.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDF
Protein Name peptide deformylase (mitochondrial)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000288022
InnateDB Gene IDBG-547353 (PDF)
Protein Structure
UniProt Annotation
Function Removes the formyl group from the N-terminal Met of newly synthesized proteins. {ECO:0000250}.
Subcellular Localization Mitochondrion {ECO:0000305}.
Disease Associations
Tissue Specificity Ubiquitous.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005506 iron ion binding
GO:0016787 hydrolase activity
GO:0042586 peptide deformylase activity
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0008284 positive regulation of cell proliferation
GO:0018206 peptidyl-methionine modification
GO:0031365 N-terminal protein amino acid modification
Cellular Component
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID
InterPro IPR000181 Formylmethionine deformylase
IPR023635 Peptide deformylase
PFAM PF01327
PRINTS PR01576
PIRSF PIRSF004749
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9HBH1
PhosphoSite PhosphoSite-
TrEMBL A0A024R6Y3
UniProt Splice Variant
Entrez Gene 64146
UniGene
RefSeq NP_071736
HUGO HGNC:30012
OMIM
CCDS CCDS10875
HPRD 17829
IMGT
EMBL AF239156 AF322879 BC019912 CH471092
GenPept AAG33968 AAH19912 AAK15624 EAW83265 EAW83268

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca