Version 5.4
Homo sapiens Protein: SLC25A42
Summary
InnateDB Protein IDBP-39338.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC25A42
Protein Name solute carrier family 25, member 42
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000326693
InnateDB Gene IDBG-39334 (SLC25A42)
Protein Structure
UniProt Annotation
Function Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'- diphosphate. {ECO:0000269PubMed:19429682}.
Subcellular Localization Mitochondrion inner membrane {ECO:0000269PubMed:19429682}; Multi-pass membrane protein {ECO:0000269PubMed:19429682}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005347 ATP transmembrane transporter activity
GO:0015217 ADP transmembrane transporter activity
GO:0015228 coenzyme A transmembrane transporter activity
GO:0043262 adenosine-diphosphatase activity
GO:0080122 AMP transmembrane transporter activity
Biological Process
GO:0008152 metabolic process
GO:0015866 ADP transport
GO:0015867 ATP transport
GO:0035349 coenzyme A transmembrane transport
GO:0080121 AMP transport
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002067 Mitochondrial carrier protein
IPR002167 Graves disease carrier protein
IPR018108 Mitochondrial substrate/solute carrier
IPR023395 Mitochondrial carrier domain
PFAM PF00153
PRINTS PR00926
PR00928
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86VD7
PhosphoSite PhosphoSite-Q86VD7
TrEMBL A0A024R7K2
UniProt Splice Variant
Entrez Gene 284439
UniGene Hs.638088
RefSeq NP_848621
HUGO HGNC:28380
OMIM 610823
CCDS CCDS32966
HPRD 17523
IMGT
EMBL AC002126 AC004143 BC045598 CH471106 FN356975
GenPept AAB86983 AAC02758 AAH45598 CAX94853 EAW84777 EAW84778

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca