Version 5.4
Homo sapiens Protein: FREM3
Summary
InnateDB Protein IDBP-39461.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FREM3
Protein Name FRAS1 related extracellular matrix 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000332886
InnateDB Gene IDBG-39459 (FREM3)
Protein Structure
UniProt Annotation
Function Extracellular matrix protein which may play a role in cell adhesion. {ECO:0000250}.
Subcellular Localization Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0046872 metal ion binding
Biological Process
GO:0007154 cell communication
GO:0007155 cell adhesion
Cellular Component
GO:0005604 basement membrane
GO:0005615 extracellular space
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031012 extracellular matrix
Protein Structure and Domains
PDB ID
InterPro IPR003644 Na-Ca exchanger/integrin-beta4
IPR015919 Cadherin-like
PFAM PF03160
PRINTS
PIRSF
SMART SM00237
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P0C091
PhosphoSite PhosphoSite-P0C091
TrEMBL
UniProt Splice Variant
Entrez Gene 166752
UniGene Hs.252714
RefSeq NP_001161707
HUGO HGNC:25172
OMIM 608946
CCDS CCDS54808
HPRD
IMGT
EMBL AC139713
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca