Version 5.4
Homo sapiens Protein: OMG
Summary
InnateDB Protein IDBP-39627.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OMG
Protein Name oligodendrocyte myelin glycoprotein
Synonyms OMGP;
Species Homo sapiens
Ensembl Protein ENSP00000247271
InnateDB Gene IDBG-39625 (OMG)
Protein Structure
UniProt Annotation
Function Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.
Subcellular Localization Cell membrane; Lipid-anchor, GPI-anchor.
Disease Associations
Tissue Specificity Oligodendrocytes and myelin of the central nervous system.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0007155 cell adhesion
GO:0031102 neuron projection regeneration
GO:0048011 neurotrophin TRK receptor signaling pathway
GO:0048683 regulation of collateral sprouting of intact axon in response to injury
GO:0050770 regulation of axonogenesis
GO:0050771 negative regulation of axonogenesis
Cellular Component
GO:0005886 plasma membrane
GO:0031225 anchored component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000372 Leucine-rich repeat-containing N-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
PFAM PF01462
PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00013
SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P23515
PhosphoSite PhosphoSite-P23515
TrEMBL
UniProt Splice Variant
Entrez Gene 4974
UniGene Hs.729594
RefSeq NP_002535
HUGO HGNC:8135
OMIM 164345
CCDS CCDS11265
HPRD 01257
IMGT
EMBL BC018050 CH471147 M63623 X51694 X57436
GenPept AAA59970 AAH18050 CAA35991 CAA40684 EAW80279 EAW80280

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca