InnateDB Protein
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IDBP-39770.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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RPS26
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Protein Name
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ribosomal protein S26
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Synonyms
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DBA10; S26;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000348849
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InnateDB Gene
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IDBG-39768 (RPS26)
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Protein Structure
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Function |
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Subcellular Localization |
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Disease Associations |
Diamond-Blackfan anemia 10 (DBA10) [MIM:613309]: A form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. {ECO:0000269PubMed:20116044}. Note=The disease is caused by mutations affecting the gene represented in this entry.
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 126 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
126
[view]
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Protein-Protein |
124
[view]
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Protein-DNA |
2
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000892
Ribosomal protein S26e
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PFAM |
PF01283
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P62854
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PhosphoSite |
PhosphoSite-P62854
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TrEMBL |
Q76N57
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UniProt Splice Variant |
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Entrez Gene |
6231
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UniGene |
Hs.668034
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RefSeq |
XP_005276741
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HUGO |
HGNC:10414
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OMIM |
603701
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CCDS |
CCDS31832
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HPRD |
04743
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IMGT |
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EMBL |
AB007160
AB007161
BC002604
BC015832
BC070220
BC105276
BC105798
CH471054
CH471057
U41448
X69654
X77770
X79236
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GenPept |
AAC26987
AAH02604
AAH15832
AAH70220
AAI05277
AAI05799
BAA25823
BAA25824
CAA49345
CAA54808
CAA55818
EAW96876
EAW96878
EAX06294
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