InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Osbpl5

Summary

InnateDB Protein

IDBP-400112.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Osbpl5

Protein Name

oxysterol binding protein-like 5

Synonyms

1110006M06Rik; AI462538; Obph1; ORP5; Osbp2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113362

InnateDB Gene

IDBG-212815 (Osbpl5)

Protein Structure

UniProt Annotation

Function

May cooperate with NPC1 to mediate the exit of cholesterol from endosomes/lysosomes. {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008289	lipid binding
GO:0015485	cholesterol binding

Biological Process

GO:0006869

lipid transport

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1930265

InterPro

IPR000648 Oxysterol-binding protein
IPR001849 Pleckstrin homology domain

PFAM

PF01237
PF00169

PRINTS

PIRSF

SMART

SM00233

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9ER64

PhosphoSite

PhosphoSite-Q9ER64

TrEMBL

D3YWU9

UniProt Splice Variant

Entrez Gene

79196

UniGene

Mm.21199

RefSeq

NP_001186156

MGI ID

MGI Symbol

Osbpl5

OMIM

CCDS

CCDS57598

HPRD

IMGT

EMBL

AB074008 AC068006 AC158299 AJ276505 AJ278263 BC079872

GenPept

AAH79872 BAB85687 CAC16404 CAC27351