InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Osbpl5

Summary

InnateDB Protein

IDBP-400113.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Osbpl5

Protein Name

oxysterol binding protein-like 5

Synonyms

1110006M06Rik; AI462538; Obph1; ORP5; Osbp2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113375

InnateDB Gene

IDBG-212815 (Osbpl5)

Protein Structure

UniProt Annotation

Function

May cooperate with NPC1 to mediate the exit of cholesterol from endosomes/lysosomes. {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008289	lipid binding
GO:0015485	cholesterol binding

Biological Process

GO:0006869

lipid transport

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1930265

InterPro

IPR000648 Oxysterol-binding protein
IPR001849 Pleckstrin homology domain

PFAM

PF01237
PF00169

PRINTS

PIRSF

SMART

SM00233

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9ER64

PhosphoSite

PhosphoSite-Q9ER64

TrEMBL

D3YWU9

UniProt Splice Variant

Entrez Gene

79196

UniGene

Mm.21199

RefSeq

MGI ID

MGI Symbol

Osbpl5

OMIM

CCDS

CCDS57598

HPRD

IMGT

EMBL

AB074008 AC068006 AC158299 AJ276505 AJ278263 BC079872

GenPept

AAH79872 BAB85687 CAC16404 CAC27351