Version 5.4
Mus musculus Protein: Prss53
Summary
InnateDB Protein IDBP-400184.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prss53
Protein Name protease, serine, 53
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000112972
InnateDB Gene IDBG-210430 (Prss53)
Protein Structure
UniProt Annotation
Function In vitro can degrade the fibrinogen alpha chain of as well as pro-urokinase-type plasminogen activator. {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:2652890
InterPro IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
IPR015420 Peptidase S1A, nudel
PFAM PF00089
PF09342
PRINTS PR00722
PIRSF
SMART SM00020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q571E5
PhosphoSite PhosphoSite-
TrEMBL B2RX64
UniProt Splice Variant
Entrez Gene 330657
UniGene Mm.489767
RefSeq NP_001074737
MGI ID
MGI Symbol Prss53
OMIM
CCDS CCDS52409
HPRD
IMGT
EMBL AK220244 BC039632 BC147509 BC151010 BC151017 CH466531
GenPept AAH39632 AAI47510 AAI51011 AAI51018 BAD90169 EDL17598

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca