InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pef1

Summary

InnateDB Protein

IDBP-400187.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pef1

Protein Name

penta-EF hand domain containing 1

Synonyms

2600002E23Rik; Peflin;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000112638

InnateDB Gene

IDBG-192445 (Pef1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated in the presence of Ca(2+). {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004198	calcium-dependent cysteine-type endopeptidase activity
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding
GO:0046982	protein heterodimerization activity
GO:0046983	protein dimerization activity

Biological Process

GO:0006508	proteolysis
GO:0051592	response to calcium ion

Cellular Component

GO:0005737	cytoplasm
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1915148

InterPro

IPR002048 EF-hand domain

PFAM

PF00036
PF13202
PF13405

PRINTS

PIRSF

SMART

SM00054

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8BFY6

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

67898

UniGene

Mm.20818

RefSeq

MGI ID

MGI Symbol

Pef1

OMIM

CCDS

CCDS18706

HPRD

IMGT

EMBL

AK007394 AK013238 AK046247 AK075978 BC019191

GenPept

AAH19191 BAB25010 BAB28735 BAC32654 BAC36091