InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pgap2

Summary

InnateDB Protein

IDBP-400358.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pgap2

Protein Name

post-GPI attachment to proteins 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113574

InnateDB Gene

IDBG-202705 (Pgap2)

Protein Structure

UniProt Annotation

Function

Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface (By similarity). {ECO:0000250}.

Subcellular Localization

Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008565	protein transporter activity

Biological Process

GO:0006506	GPI anchor biosynthetic process
GO:0006974	cellular response to DNA damage stimulus
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
GO:0015031	protein transport
GO:0042770	signal transduction in response to DNA damage
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage