InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Atg16l2

Summary

InnateDB Protein

IDBP-400387.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Atg16l2

Protein Name

autophagy related 16 like 2 (S. cerevisiae)

Synonyms

2410118P20Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000112500

InnateDB Gene

IDBG-201840 (Atg16l2)

Protein Structure

UniProt Annotation

Function

May play a role in autophagy. {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Note=Localizes also to discrete punctae along the ciliary axoneme. {ECO:0000269PubMed:24089209}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0006914	autophagy
GO:0015031	protein transport
GO:0039689	negative stranded viral RNA replication

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:1920933

InterPro

IPR001680 WD40 repeat
IPR013923 Autophagy-related protein 16
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat

PFAM

PF00400
PF08614

PRINTS

PR00320

PIRSF

SMART

SM00320

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q6KAU8

PhosphoSite

PhosphoSite-Q6KAU8

TrEMBL

G9M4M8

UniProt Splice Variant

Entrez Gene

73683

UniGene

RefSeq

NP_001104581

MGI ID

MGI Symbol

Atg16l2

OMIM

CCDS

CCDS52329

HPRD

IMGT

EMBL

AB476648 AC107638 AK131109 BC060054

GenPept

AAH60054 BAD21359 BAL42360