InnateDB Protein
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IDBP-400391.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Emcn
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Protein Name
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endomucin
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Synonyms
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0610012K22Rik; AI315669; Muc14;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000114102
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InnateDB Gene
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IDBG-195850 (Emcn)
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Protein Structure
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Function |
Endothelial sialomucin, also called endomucin or mucin- like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. {ECO:0000250}.
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Subcellular Localization |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Highly expressed in heart and kidney, followed by brain, spleen, thymus, liver and lung. Exclusively expressed in endothelial cells. {ECO:0000269PubMed:11418125}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
2 [view]
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|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1891716
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InterPro |
IPR010740
Endomucin
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PFAM |
PF07010
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9R0H2
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PhosphoSite |
PhosphoSite-Q9R0H2
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
59308
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UniGene |
Mm.414987
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RefSeq |
NP_058581
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MGI ID |
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MGI Symbol |
Emcn
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OMIM |
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CCDS |
CCDS17861
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HPRD |
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IMGT |
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EMBL |
AB034693
AB034694
AF060883
AK002616
BC003706
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GenPept |
AAD05208
AAH03706
BAA86226
BAA86227
BAB22232
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