InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dram2

Summary

InnateDB Protein

IDBP-400609.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dram2

Protein Name

VDNA-damage regulated autophagy modulator 2

Synonyms

2010305N14Rik; 2610318G18Rik; AI647667; Tmem77;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113069

InnateDB Gene

IDBG-184812 (Dram2)

Protein Structure

UniProt Annotation

Function

Induces apoptotic cell death when coexpressed with DRAM1. {ECO:0000250}.

Subcellular Localization

Lysosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0030262	apoptotic nuclear changes
GO:0097194	execution phase of apoptosis

Cellular Component

GO:0005764	lysosome
GO:0005765	lysosomal membrane
GO:0005794	Golgi apparatus
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1914421

InterPro

IPR019402 Frag1/DRAM/Sfk1

PFAM

PF10277

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9CR48

PhosphoSite

PhosphoSite-

TrEMBL

D3Z6B7

UniProt Splice Variant

Entrez Gene

67171

UniGene

Mm.472019

RefSeq

MGI ID

MGI Symbol

Dram2

OMIM

CCDS

CCDS17725

HPRD

IMGT

EMBL

AC117200 AK009940 AK012044 AK015888 AK052824 AK172455

GenPept

BAB26598 BAB27990 BAB30020 BAC35162 BAE43014