InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cept1

Summary

InnateDB Protein

IDBP-400612.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cept1

Protein Name

choline/ethanolaminephosphotransferase 1

Synonyms

9930118K05Rik; mCEPT1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000112509

InnateDB Gene

IDBG-184709 (Cept1)

Protein Structure

UniProt Annotation

Function

Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP- ethanolamine, respectively. Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity (By similarity). {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Nucleus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004142	diacylglycerol cholinephosphotransferase activity
GO:0004307	ethanolaminephosphotransferase activity
GO:0016780	phosphotransferase activity, for other substituted phosphate groups
GO:0046872	metal ion binding

Biological Process

GO:0006646	phosphatidylethanolamine biosynthetic process
GO:0006656	phosphatidylcholine biosynthetic process
GO:0006657	CDP-choline pathway
GO:0008654	phospholipid biosynthetic process