InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Zdhhc13

Summary

InnateDB Protein

IDBP-400662.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Zdhhc13

Protein Name

zinc finger, DHHC domain containing 13

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000112498

InnateDB Gene

IDBG-187601 (Zdhhc13)

Protein Structure

UniProt Annotation

Function

Palmitoyltransferase for HD and GAD2. Mediates Mg(2+) transport. {ECO:0000269PubMed:18794299, ECO:0000269PubMed:19299482}.

Subcellular Localization

Golgi apparatus membrane {ECO:0000269PubMed:18794299}; Multi-pass membrane protein {ECO:0000269PubMed:18794299}. Cytoplasmic vesicle membrane {ECO:0000269PubMed:18794299}; Multi-pass membrane protein {ECO:0000269PubMed:18794299}. Note=Low extracellular Mg(2+) induces increase in Golgi and in post-Golgi vesicles.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0015095	magnesium ion transmembrane transporter activity
GO:0016409	palmitoyltransferase activity
GO:0019706	protein-cysteine S-palmitoyltransferase activity

Biological Process

GO:0007165	signal transduction
GO:0008152	metabolic process
GO:0015693	magnesium ion transport
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

Cellular Component

GO:0000139	Golgi membrane
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030660	Golgi-associated vesicle membrane
GO:0043231	intracellular membrane-bounded organelle