Version 5.4
Mus musculus Protein: Paics
Summary
InnateDB Protein IDBP-400764.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Paics
Protein Name phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase
Synonyms 2610511I09Rik; ADE2H1; AIRC; PAIS;
Species Mus musculus
Ensembl Protein ENSMUSP00000113483
InnateDB Gene IDBG-173676 (Paics)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 43 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 43 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004638 phosphoribosylaminoimidazole carboxylase activity
GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0005524 ATP binding
GO:0042802 identical protein binding
Biological Process
GO:0006189 'de novo' IMP biosynthetic process
Cellular Component
Protein Structure and Domains
PDB ID MGI:1914304
InterPro IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain
IPR028923 SAICAR synthetase/ADE2, N-terminal
PFAM PF00731
PF01259
PRINTS
PIRSF
SMART SM01001
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9DCL9
PhosphoSite PhosphoSite-Q9DCL9
TrEMBL D3Z6P1
UniProt Splice Variant
Entrez Gene 67054
UniGene Mm.475564
RefSeq XP_006535243
MGI ID
MGI Symbol Paics
OMIM
CCDS CCDS19367
HPRD
IMGT
EMBL AC114666 AK002669 AK010462 AK012118 AK146722 AK159398 AK166264 BC018153 BC052691 CH466524
GenPept AAH18153 AAH52691 BAB22273 BAB26957 BAB28044 BAE27385 BAE35051 BAE38669 EDL37918

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca