InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lonp2

Summary

InnateDB Protein

IDBP-400850.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lonp2

Protein Name

lon peptidase 2, peroxisomal

Synonyms

1300002A08Rik; AU015403; Lonp;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113381

InnateDB Gene

IDBG-177971 (Lonp2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002020	protease binding
GO:0004176	ATP-dependent peptidase activity
GO:0004252	serine-type endopeptidase activity
GO:0005102	receptor binding
GO:0005515	protein binding
GO:0005524	ATP binding

Biological Process

GO:0006200	ATP catabolic process
GO:0006465	signal peptide processing
GO:0006508	proteolysis
GO:0006515	misfolded or incompletely synthesized protein catabolic process
GO:0006625	protein targeting to peroxisome
GO:0014070	response to organic cyclic compound
GO:0016485	protein processing
GO:0031998	regulation of fatty acid beta-oxidation

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005782	peroxisomal matrix

Protein Structure and Domains

PDB ID

MGI:1914137

InterPro

IPR003959 ATPase, AAA-type, core
IPR008269 Peptidase S16, Lon C-terminal
IPR020568 Ribosomal protein S5 domain 2-type fold
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00004
PF07724
PF13304
PF05362

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-