Mus musculus Protein: Adamtsl4 | |||||||||
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Summary | |||||||||
InnateDB Protein | IDBP-400912.4 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | Adamtsl4 | ||||||||
Protein Name | ADAMTS-like 4 | ||||||||
Synonyms | |||||||||
Species | Mus musculus | ||||||||
Ensembl Protein | ENSMUSP00000113424 | ||||||||
InnateDB Gene | IDBG-173246 (Adamtsl4) | ||||||||
Protein Structure | |||||||||
UniProt Annotation | |||||||||
Function | Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis (By similarity). {ECO:0000250}. | ||||||||
Subcellular Localization | Secreted, extracellular space, extracellular matrix {ECO:0000250}. Note=Colocalizes with FMN1 microfibrils in the eye ECM. {ECO:0000250}. | ||||||||
Disease Associations | |||||||||
Tissue Specificity | Widely expressed in a range of tissues. Especially prevalent in brain, spinal cord, muscle, lung and heart. {ECO:0000269PubMed:12706885}. | ||||||||
Comments | |||||||||
Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||
PDB ID | MGI:2389008 | ||||||||
InterPro |
IPR000884
Thrombospondin, type 1 repeat IPR010294 ADAM-TS Spacer 1 IPR010909 PLAC |
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PFAM |
PF00090
PF05986 PF08686 |
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PRINTS | |||||||||
PIRSF | |||||||||
SMART |
SM00209
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TIGRFAMs | |||||||||
Post-translational Modifications | |||||||||
Modification | |||||||||
Cross-References | |||||||||
SwissProt | Q80T21 | ||||||||
PhosphoSite | PhosphoSite-Q80T21 | ||||||||
TrEMBL | Q91YP4 | ||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 229595 | ||||||||
UniGene | Mm.490574 | ||||||||
RefSeq | XP_006501430 | ||||||||
MGI ID | |||||||||
MGI Symbol | Adamtsl4 | ||||||||
OMIM | |||||||||
CCDS | CCDS17618 | ||||||||
HPRD | |||||||||
IMGT | |||||||||
EMBL | AY158701 BC016215 BC117925 | ||||||||
GenPept | AAH16215 AAI17926 AAO17738 | ||||||||